The X-Men band together to find a mutant assassin who has made an attempt on the President's life, while the Mutant Academy is attacked by military forces.
In 1962, the United States government enlists the help of Mutants with superhuman abilities to stop a malicious dictator who is determined to start World War III.
When a cure is found to treat mutations, lines are drawn amongst the X-Men, led by Professor Charles Xavier, and the Brotherhood, a band of powerful mutants organized under Xavier's former ally, Magneto.